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Happy New Year from Discngine 🎉

Discngine-Voeux2026

May this year bring meaningful progress, innovation, and continued collaboration in early drug discovery. 🧬

 

As we step into 2026, we look forward to continuing to provide you with industry insights, product updates, events, engaging articles, and more.

đź“… Event | Join us in Basel for the Discngine Labs Live event!

Discngine Labs Basel 2026 promo FINAL

Navigating developability challenges across advanced modalities: Computational tools & approaches

đź“… Tuesday, March 17, 2026

đź•“ 3:00 PM (CET)

📍Hyperion Hotel, Basel, Switzerland (& virtual)

Join us for the first 2026 edition of Discngine Labs, held both in-person and live. This session will explore how in-silico approaches are evolving to address complex antibody modalities and enhance their developability assessment.

 

The event will feature experts from leading pharma companies, including a keynote by Bruck Taddese from Novartis Biologics Research Center and a roundtable chaired by Tarik Khan from Roche.

See agenda, speakers and register here 👉

📢 Product News | 3dpredict/Ab release

CST overview tab

We have released a new update to 3dpredict/Ab, our tool for ensemble-based antibody structure and property prediction.

This release introduces a built-in reference set of 1000 clinical-stage antibodies, sourced from public databases and processed through 3dpredict/Ab for consistent property prediction.

Discovery teams will now be able to evaluate predicted properties for new candidates within a clinical antibody landscape, supporting more informed developability decisions.

Explore full release notes
Learn about 3dpredict/Ab

📢 Product News | Ideation SAR Slides 2.6 release

Ideation SAR Slides new feature

Ideation SAR Slides 2.6 is now available! This release introduces Dataset Templating, a new capability that applies existing dataset configurations to new uploads so endpoints and their settings are ready immediately. This streamlines dataset onboarding and reduces manual setup.

This new version also brings other enhancements to usability and data handling.

Learn more in the release notes

More exciting news is coming very soon. Stay tuned for what’s next!

📢 Coming Soon | Enhanced Pocket Similarity Search in 3decision

Pocket similarity search

We will soon reveal a new update for 3decision, our protein structure repository for data management and analysis.

We are improving its Pocket Similarity Search feature for accurate detection and analysis of similar binding pockets.

The updated version introduces new capabilities for searching, visualizing, and comparing results across structures.

Stay tuned!

➡️ Happening now | Meet us in San Diego, CA

BioLogic Summit + PepTalk 2026

Join us from January 19-22 at the annual BioLogic Summit and the co-located PepTalk conference. We will be on site with colleagues from Chemical Computing Group (CCG) at booth #520.

We look forward to connecting with the biologics community, sharing insights, and exploring collaborations. If you're attending, let’s connect!

>> Read more

You can also meet us at the Happy Hour networking event we are organizing with SAGIM (Southern California Area Group for Informatics and Modeling) on January 20 from 5:00 to 8:00 PM. 

>> Register here for free

Highlights from Discngine Meetup Vol.5 on Peptide Discovery 

Explore the main takeaways and session recordings from our 5th Discngine Meetup in our latest blog post. Featured experts from AstraZeneca, Merck, Novartis, and Chemical Computing Group shared insights and challenges in peptide design and discovery.

>> Read the full article here
cyclic peptide dark background

Menin

Protein of the Month: Menin

We examined Menin’s emerging importance as a target for cancer treatment. After having long been considered difficult to drug, it became a viable target with the development and approval of an effective Menin inhibitor for certain forms of leukemia.

>> Discover Menin's story and structural insights

Useful Links

3decision Science Blog

Protein of the Month

Discngine Blog

Discngine YouTube Channel

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